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All South America Cruises

All aboard for a spectacular cruising adventure discovering the treasures of South America, Argentina, Chile & Patagonia. Click here if you are interested in an Antarctic cruise departing from South America. Choose from 2,248 expeditions and cruises around South America travelling with the world's leading cruise lines.
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134 Days
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387 Cruises (2,248 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Jun 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Earlybird Saving
Save (per person) 322
From (per person) 16,907
View Trip
10 Day Complete Galapagos (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Oct 2024 to Dec 2026
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save (per person) 1,612
From (per person) 8,799
View Trip
7 Day Galapagos Explorer: Southern Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

7 Days (6 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Oct 2024 to Dec 2026
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save (per person) 1,073
From (per person) 5,744
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departure: 01 March 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save (per person) 1,544
From (per person) 17,851
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 20 February 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save (per person) 1,546
From (per person) 17,649
View Trip
13 Day Treasures of Galapagos: Western & Central Islands (Grand Queen Beatriz) with Intrepid Travel
Cruise
 (1)

13 Days (12 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Oct 2024 to Dec 2026
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save (per person) 2,221
From (per person) 11,887
View Trip
10 Day Ultimate Galapagos: Central Islands (Grand Daphne) with Intrepid Travel
Cruise
 (1)

10 Days (9 Nights) Quito to Quito
Operated By: Intrepid Travel
Departures: Nov 2024 to Dec 2026
Countries Visited: Ecuador, Galapagos
Limited Time Sale
Save (per person) 1,612
From (per person) 8,799
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jan 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Earlybird Saving
Save (per person) 305
From (per person) 14,515
View Trip
15 Day South America Passage with Holland America
Cruise
 (2)

15 Days (14 Nights) Buenos Aires to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departure: 08 March 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Exclusive DealHave It All Offer
INSIDE
$2,430
OCEANVIEW
$2,672
BALCONY
$3,691
SUITE
$4,509
From (per person) 2,430
View Trip
10 Day Ocean Voyage: Hanga Roa - Ushuaia with Ponant
Cruise
 (1)

10 Days (9 Nights) Hanga Roa to Ushuaia
Cruise Line: Ponant
Ship: Le Boreal
Departure: 05 November 2024
Countries Visited: Easter Island, Argentina
Exclusive Savings
INSIDE
-
OCEANVIEW
$3,296
BALCONY
$3,551
SUITE
$5,315
Save (per person) 54
From (per person) 3,296
View Trip
6 Day South America with MSC Cruises
Cruise
 (1)

6 Days (5 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 09 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$906
OCEANVIEW
$1,012
BALCONY
$1,197
SUITE
$2,138
From (per person) 906
View Trip
7 Day South America with MSC Cruises
Cruise
 (1)

7 Days (6 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 February 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$969
OCEANVIEW
$1,095
BALCONY
$1,299
SUITE
$2,395
From (per person) 969
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 02 March 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,381
OCEANVIEW
$1,546
BALCONY
$1,779
SUITE
$3,049
From (per person) 1,381
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Nov 2024 to Dec 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$685
OCEANVIEW
$733
BALCONY
$820
SUITE
$1,451
From (per person) 685
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (3)

18 Days (17 Nights) Santiago to Buenos Aires
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Nov 2024 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$19,595
Save (per person) 1,123
From (per person) 9,895
View Trip
18 Day Inca & Panama Canal Discovery with Holland America
Cruise
 (2)

18 Days (17 Nights) San Antonio to Fort Lauderdale
Cruise Line: Holland America
Ship: Oosterdam
Departures: Mar 2025 to Mar 2026
Countries Visited: Chile, Peru, Ecuador, Panama (+2 more), Cayman Islands, USA
Exclusive DealHave It All Offer
INSIDE
$2,926
OCEANVIEW
$3,074
BALCONY
$4,108
SUITE
$5,282
From (per person) 2,926
View Trip
18 Day South America & the Chilean Fjords with Viking Cruises
Cruise
 (3)

18 Days (17 Nights) Buenos Aires to Santiago
Cruise Line: Viking Cruises
Ship: Viking Jupiter
Departures: Dec 2024 to Feb 2026
Countries Visited: Argentina, Uruguay, Falkland Islands, Chile
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$9,895
SUITE
$20,183
Save (per person) 1,100
From (per person) 9,895
View Trip
4 Day South America with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Feb 2025 to Feb 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$617
OCEANVIEW
$675
BALCONY
$791
SUITE
$1,451
From (per person) 617
View Trip
14 Day Chile, Peru & Panama Voyage with Azamara Cruises
Cruise
 (1)

14 Days (13 Nights) San Antonio to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 March 2026
Countries Visited: Chile, Peru, Panama
INSIDE
$6,252
OCEANVIEW
$7,598
BALCONY
$8,984
SUITE
$10,519
From (per person) 6,252
View Trip
26 Day Carnival Rio & Amazon Voyage with Azamara Cruises
Cruise
 (1)

26 Days (25 Nights) Buenos Aires to Bridgetown
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 25 February 2025
Countries Visited: Argentina, Uruguay, Brazil, French Guiana (+1 more), Barbados
Circle Club Voyage
INSIDE
$11,550
OCEANVIEW
$11,372
BALCONY
$15,114
SUITE
$47,893
From (per person) 11,372
View Trip
20 Day Falklands, South Georgia & Valdes Peninsula: In The Heart Of The Wilderness with Ponant
Cruise
 (1)

20 Days (19 Nights) Buenos Aires to Buenos Aires
Cruise Line: Ponant
Ship: Le Boreal
Departure: 11 March 2025
Countries Visited: Argentina, Falkland Islands, South Georgia Island
Exclusive Savings
INSIDE
-
OCEANVIEW
$17,393
BALCONY
$19,402
SUITE
$28,614
Save (per person) 327
From (per person) 17,393
View Trip
32 Day Panama Canal, Inca & South America Discovery with Holland America
Cruise
 (2)

32 Days (31 Nights) Fort Lauderdale to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departure: 17 November 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+5 more), Peru, Chile, Argentina, Falkland Islands, Uruguay
Exclusive DealHave It All Offer
INSIDE
$4,896
OCEANVIEW
$5,312
BALCONY
$7,003
SUITE
$8,827
From (per person) 4,896
View Trip
16 Day Cape Horn & Strait of Magellan with Princess
Cruise
 (3)

16 Days (15 Nights) Santiago to Buenos Aires
Cruise Line: Princess
Ship: Majestic Princess
Departure: 19 December 2024
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$5,281
SUITE
$6,073
From (per person) 5,281
View Trip
18 Day Panama Canal & Inca Discovery with Holland America
Cruise
 (2)

18 Days (17 Nights) Fort Lauderdale to San Antonio
Cruise Line: Holland America
Ship: Oosterdam
Departures: Nov 2024 to Nov 2025
Countries Visited: USA, Cayman Islands, Panama, Ecuador (+2 more), Peru, Chile
Mutiple Deals Available
INSIDE
$2,550
OCEANVIEW
$2,708
BALCONY
$3,688
SUITE
$5,218
From (per person) 2,550
View Trip
11 Day Peru & Chile Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Lima to San Antonio
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 23 January 2025
Countries Visited: Peru, Chile
Circle Club Voyage
INSIDE
$2,892
OCEANVIEW
$2,981
BALCONY
$4,020
SUITE
$8,525
From (per person) 2,892
View Trip
15 Day South America Passage with Holland America
Cruise
 (2)

15 Days (14 Nights) San Antonio to Buenos Aires
Cruise Line: Holland America
Ship: Oosterdam
Departures: Dec 2025 to Feb 2026
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay
Exclusive DealHave It All Offer
INSIDE
$2,222
OCEANVIEW
$2,499
BALCONY
$3,414
SUITE
$4,058
From (per person) 2,222
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 28 December 2024
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$2,433
OCEANVIEW
$2,578
BALCONY
$2,966
SUITE
$4,673
From (per person) 2,433
View Trip
9 Day South America with MSC Cruises
Cruise
 (1)

9 Days (8 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departures: Dec 2024 to Jan 2025
Countries Visited: Brazil, Argentina, Uruguay
Save And Sail OfferEarly Booking Offer
INSIDE
$1,492
OCEANVIEW
$1,608
BALCONY
$1,793
SUITE
$3,306
From (per person) 1,492
View Trip
8 Day South America with MSC Cruises
Cruise
 (1)

8 Days (7 Nights) Rio de Janeiro to Rio de Janeiro
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 08 February 2025
Countries Visited: Brazil
Save And Sail OfferEarly Booking Offer
INSIDE
$1,090
OCEANVIEW
$1,274
BALCONY
$1,507
SUITE
$2,778
From (per person) 1,090
View Trip
23 Day Barbados To Brazil & Buenos Aires Voyage with Azamara Cruises
Cruise
 (1)

23 Days (22 Nights) Bridgetown to Buenos Aires
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 17 January 2026
Countries Visited: Barbados, Trinidad and Tobago, French Guiana, Brazil (+2 more), Uruguay, Argentina
INSIDE
$9,092
OCEANVIEW
$10,864
BALCONY
$13,676
SUITE
$17,358
From (per person) 9,092
View Trip
Results: 1-30 of 387

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South & Central America Cruises

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Travel Styles

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Cities

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Routes

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Country Routes

Cruises from Peru to Argentina Cruises from USA to Portugal Cruises from USA to Germany Cruises from Italy to England Cruises from Germany to England Cruises from France to Spain Cruises from Portugal to England Cruises from Puerto Rico to USA Cruises from France to Brazil Cruises from France to USA Cruises from England to Canada Cruises from England to Germany Cruises from Dominican Republic to USA Cruises from Brazil to Spain Cruises from USA to Puerto Rico Cruises from Canada to England Cruises from Argentina to Brazil Cruises from Argentina to Chile Cruises from Brazil to Italy Cruises from Argentina to USA Cruises from Barbados to USA Cruises from Brazil to Argentina Cruises from Canada to USA Cruises from Chile to Argentina Cruises from England to Denmark Cruises from England to Italy Cruises from England to Spain Cruises from England to USA Cruises from France to Italy Cruises from Italy to Brazil Cruises from Italy to France Cruises from Italy to Portugal Cruises from Italy to Spain Cruises from Italy to USA Cruises from Panama to USA Cruises from Spain to Brazil Cruises from Peru to Ecuador Cruises from Portugal to Italy Cruises from Portugal to Spain Cruises from Portugal to USA Cruises from Spain to France Cruises from Spain to Italy Cruises from Spain to Portugal Cruises from Spain to USA Cruises from USA to Argentina Cruises from USA to Australia Cruises from USA to Barbados Cruises from USA to Canada Cruises from USA to England Cruises from USA to French Polynesia Cruises from USA to Holland Cruises from USA to Italy Cruises from Spain to England Cruises from USA to Panama Cruises from USA to Peru Cruises from USA to Spain

Cruise Lines Exploring South & Central America

Azamara South America Cruises Celebrity Central America Cruises Cunard Central America Cruises HX Hurtigruten South America Expeditions MSC South America Cruises NCL Central America Cruises Oceania South America Cruises Ponant Central America Cruises Ponant South America Cruises Princess South America Cruises Regent Seven Seas South America Cruises Royal Caribbean Central America Cruises Seabourn South America Cruises Silversea South America Cruises Viking South America Cruises Viking Central America Cruises

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