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Sicily Cruises

Are you looking for a cruise to Sicily? Choose from 275 unique cruise itineraries to Sicily, departing from Amalfi, Antalya, Athens, Barcelona, Bologna and more. September is the most popular month to cruise to Sicily and we have over 1,700 departures available from twenty-two of the world's leading cruise lines.
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275 Cruises (1,700 Cruise Departures)
8 Day Greece & Italy Cruise with Royal Caribbean
Cruise
 (2)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Royal Caribbean
Ship: Brilliance of the Seas
Departure: 15 August 2025
Countries Visited: Greece, Sicily, Spain
Exclusive Deal
INSIDE
$1,663
OCEANVIEW
$1,882
BALCONY
$2,625
SUITE
$3,288
Save (per person) 782
From (per person) 1,663
View Trip
10 Day Greek Isles & Italy with Norwegian Cruise Line
Cruise
 (1)

10 Days (9 Nights) Rome to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departure: 22 September 2025
Countries Visited: Italy, Greece, Sicily
More At Sea Offer
INSIDE
$3,655
OCEANVIEW
-
BALCONY
$5,827
SUITE
$6,591
From (per person) 3,655
View Trip
10 Day Italy, between the Adriatic Sea & the Ionian Sea with Ponant
Cruise
 (1)

10 Days (9 Nights) Venice to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 24 September 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Savings
INSIDE
-
OCEANVIEW
$7,795
BALCONY
$8,226
SUITE
$15,439
Save (per person) 145
From (per person) 7,795
View Trip
8 Day Authentic Shores of Sicily with Ponant
Cruise
 (1)

8 Days (7 Nights) Valletta to Valletta
Cruise Line: Ponant
Ship: Le Boreal
Departure: 03 October 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
$6,077
BALCONY
$6,400
SUITE
$12,006
Save (per person) 113
From (per person) 6,077
View Trip
8 Day Glorious Greek Isles to Spanish Sunsets with Virgin Voyages
Cruise
 (5)

8 Days (7 Nights) Athens to Barcelona
Cruise Line: Virgin Voyages
Ships: Resilient Lady, Scarlet Lady
Departures: Oct 2025 to Oct 2026
Countries Visited: Greece, Sicily, Spain
70% Off Second Sailor + Save
INSIDE
$2,356
OCEANVIEW
$2,765
BALCONY
$3,078
SUITE
$6,332
From (per person) 2,356
View Trip
9 Day Mind and Taste Buds Awake with the Mucem in the Mediterranean with Ponant
Cruise
 (2)

9 Days (8 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 09 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,214
SUITE
$15,486
Save (per person) 156
From (per person) 8,214
View Trip
13 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (1)

13 Days (12 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 11 April 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,685
OCEANVIEW
$6,120
BALCONY
$7,249
SUITE
-
From (per person) 5,685
View Trip
12 Day Italy Intensive Voyage with Azamara Cruises
Cruise
 (2)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 15 July 2025
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$5,357
OCEANVIEW
$5,456
BALCONY
$8,307
SUITE
$11,089
From (per person) 5,357
View Trip
9 Day Epicurean Delights of Sicily and the Adriatic Coast of Italy with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Venice
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 10 June 2025
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,439
SUITE
$21,278
Save (per person) 221
From (per person) 11,439
View Trip
9 Day A Circumnavigation of Sicily - with Smithsonian Journeys with Ponant
Cruise
 (1)

9 Days (8 Nights) Valletta to Valletta
Cruise Line: Ponant
Ships: Le Bougainville, Le Dumont d’Urville
Departures: Jun 2025 to Aug 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,694
SUITE
$18,103
Save (per person) 257
From (per person) 10,694
View Trip
12 Day Italy Cruise: Venice, Sicily & Rome with Azamara Cruises
Cruise
 (2)

12 Days (11 Nights) Rome to Venice
Cruise Line: Azamara Cruises
Ship: Azamara Onward
Departure: 22 August 2026
Countries Visited: Italy, Sicily, Montenegro
INSIDE
$4,625
OCEANVIEW
$5,288
BALCONY
$6,674
SUITE
$9,080
From (per person) 4,625
View Trip
11 Day Mediterranean Delights with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Valletta to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 20 July 2026
Countries Visited: Malta, Sicily, Tunisia
Exclusive Deal
INSIDE
-
OCEANVIEW
$10,588
BALCONY
-
SUITE
$14,548
Save (per person) 2,607
From (per person) 10,588
View Trip
11 Day Amalfi Coast, Sicily & Gulf of Naples with Emerald Cruises
New ReleaseCruise

11 Days (10 Nights) Rome to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 19 October 2024
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$14,301
Save (per person) 3,144
From (per person) 14,301
View Trip
12 Day Sicily, the Amalfi Coast & Rome - Northbound with Tauck
Cruise

12 Days (11 Nights) Valletta to Rome
Operated By: Tauck
Departures: May 2025 to Oct 2025
Countries Visited: Malta, Sicily, Italy
From (per person) 18,940
View Trip
4 Day Mediterranean with MSC Cruises
Cruise

4 Days (3 Nights) Barcelona to Palermo
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 29 April 2025
Countries Visited: Spain, Tunisia, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
$690
BALCONY
$777
SUITE
$1,097
From (per person) 690
View Trip
6 Day Mediterranean with MSC Cruises
Cruise

6 Days (5 Nights) Genoa to Valencia
Cruise Line: MSC Cruises
Ship: MSC Grandiosa
Departure: 26 April 2025
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
$989
BALCONY
$1,066
SUITE
$3,298
From (per person) 989
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Rome to Valencia
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 27 October 2024
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$620
SUITE
$901
From (per person) 620
View Trip
8 Day Mediterranean with P&O Cruises Worldwide
Cruise

8 Days (7 Nights) Valletta to Valletta
Cruise Line: P&O Cruises Worldwide
Ship: Azura
Departure: 25 September 2025
Countries Visited: Malta, Croatia, Sicily
Latest Offer
INSIDE
$2,080
OCEANVIEW
$2,565
BALCONY
$2,979
SUITE
$4,841
From (per person) 2,080
View Trip
8 Day Italian Treasures: Amalfi Coast, Sicily and Malta with Scenic
New ReleaseCruise

8 Days (7 Nights) Rome to Valletta
Cruise Line: Scenic
Ship: Scenic Eclipse II
Departure: 07 June 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$10,291
SUITE
$16,568
Save (per person) 3,104
From (per person) 10,291
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Venice to Rome
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+4 more), Viking Saturn, Viking Sea, Viking Vela, Viking Vesta
Departures: May 2025 to Sep 2026
Countries Visited: Italy, Croatia, Sicily
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,935
SUITE
$9,895
Save (per person) 2,360
From (per person) 5,935
View Trip
8 Day Greek Isles & Italy Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Rome to Rome
Cruise Line: Royal Caribbean
Ship: Odyssey of the Seas
Departure: 05 October 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
$2,032
OCEANVIEW
$2,517
BALCONY
$2,542
SUITE
$4,251
Save (per person) 977
From (per person) 2,032
View Trip
9 Day Cruising Southern Italy and Sicily - with Smithsonian Journeys with Ponant
Cruise

9 Days (8 Nights) Valletta to Livorno
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departures: Aug 2025 to Sep 2026
Countries Visited: Malta, Sicily, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$10,517
SUITE
$17,740
Save (per person) 221
From (per person) 10,517
View Trip
11 Day Ancient Civilisations, from Italy to Greece with Ponant
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Ponant
Ship: Le Champlain
Departure: 01 October 2026
Countries Visited: Italy, Sicily, Greece
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$9,531
SUITE
$17,880
Save (per person) 179
From (per person) 9,531
View Trip
11 Day 5th Opera Festival at Sea with Ponant
Cruise

11 Days (10 Nights) Venice to Nice
Cruise Line: Ponant
Ship: Le Dumont d’Urville
Departure: 22 June 2026
Countries Visited: Italy, Sicily, France
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$11,873
SUITE
$22,320
Save (per person) 227
From (per person) 11,873
View Trip
5 Day MSC Grand Voyages with MSC Cruises
Cruise

5 Days (4 Nights) Genoa to Barcelona
Cruise Line: MSC Cruises
Ship: MSC Seaside
Departure: 26 October 2024
Countries Visited: Italy, Sicily, Spain
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$697
SUITE
$998
From (per person) 697
View Trip
10 Day Malta, Sicily & Amalfi Coast with Emerald Cruises
New ReleaseCruise

10 Days (9 Nights) Rome to Valletta
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 11 July 2026
Countries Visited: Italy, Sicily, Malta
Exclusive Deal
INSIDE
-
OCEANVIEW
$9,747
BALCONY
-
SUITE
$13,261
Save (per person) 2,098
From (per person) 9,747
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Athens to Rome
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 26 July 2025
Countries Visited: Greece, Sicily, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$10,128
Save (per person) 852
From (per person) 10,128
View Trip
8 Day Italian Sojourn with Viking Cruises
Cruise

8 Days (7 Nights) Rome to Venice
Cruise Line: Viking Cruises
Ships: Viking Jupiter, Viking Mars (+5 more), Viking Saturn, Viking Sea, Viking Sky, Viking Star, Viking Vesta
Departures: Jan 2025 to Aug 2026
Countries Visited: Italy, Sicily, Croatia
Companion Fly Free
INSIDE
-
OCEANVIEW
-
BALCONY
$5,875
SUITE
$8,325
Save (per person) 176
From (per person) 5,875
View Trip
8 Day Pearls of Italy and Greece with the Corinth Canal with Emerald Cruises
Cruise

8 Days (7 Nights) Rome to Athens
Cruise Line: Emerald Cruises
Ship: Emerald Sakara
Departure: 07 June 2025
Countries Visited: Italy, Sicily, Greece
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$9,509
Save (per person) 2,096
From (per person) 9,509
View Trip
11 Day Rome, Florence, Mykonos & More with Virgin Voyages
Cruise

11 Days (10 Nights) Rome to Athens
Cruise Line: Virgin Voyages
Ship: Scarlet Lady
Departure: 31 August 2026
Countries Visited: Italy, Sicily, Greece
INSIDE
$3,375
OCEANVIEW
$4,001
BALCONY
$4,457
SUITE
$9,006
From (per person) 3,375
View Trip
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