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South America Locally Guided Cruises

Explore the best locally guided tours around South America. Choose from 24 unique cruise itineraries with 9 past traveller reviews from 3 leading cruise lines. September and October are the most popular months to join a locally guided tour around South America with 283 departures starting between October 2024 and February 2027.
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24 Cruises (283 Cruise Departures)
30 Day Ultimate South America with Brazil's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise
 (3)

30 Days Manaus to Guayaquil
Operated By: Cosmos
Departures: Jun 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Earlybird Saving
Save (per person) 322
From (per person) 16,907
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Rio de Janeiro to Lima
Operated By: Travelmarvel
Departure: 01 March 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Brazil, Argentina, Uruguay, Falkland Islands (+2 more), Chile, Peru
Exclusive Deal
Save (per person) 1,544
From (per person) 17,851
View Trip
33 Day Highlights of South America and Chilean Fjords Cruise with Travelmarvel
Tour + Cruise
 (1)

33 Days Santiago to Lima
Operated By: Travelmarvel
Departure: 20 February 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Falkland Islands, Uruguay (+2 more), Brazil, Peru
Exclusive Deal
Save (per person) 1,546
From (per person) 17,649
View Trip
26 Day Ultimate South America with a Galapagos Cruise with Cosmos
Tour + Cruise
 (1)

26 Days Rio de Janeiro to Guayaquil
Operated By: Cosmos
Departures: Jan 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador (+1 more), Galapagos
Earlybird Saving
Save (per person) 305
From (per person) 14,515
View Trip
21 Day Mysteries of the Inca Empire with Peru's Amazon & Galapagos Cruise with Cosmos
Tour + Cruise

21 Days Lima to Quito
Operated By: Cosmos
Departures: Jun 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Earlybird Saving
Save (per person) 290
From (per person) 11,942
View Trip
13 Day Peru Splendors with Galapagos Cruise with Globus
Tour + Cruise

13 Days Lima to Guayaquil
Operated By: Globus
Departures: Jan 2025 to Dec 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 187
From (per person) 10,658
View Trip
21 Day South America Revealed with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

21 Days Rio de Janeiro to Quito
Operated By: Trafalgar
Departure: 22 November 2024
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Brazil, Argentina, Peru, Ecuador
Exclusive Savings
From (per person) 19,560
View Trip
22 Day Treasures of South America with Chilean Fjords - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

22 Days Santiago to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 04 November 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Chile, Argentina, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$28,537
SUITE
$38,457
Save (per person) 6,788
From (per person) 28,537
View Trip
23 Day Legacy of the Incas with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

23 Days Lima to Guayaquil
Operated By: Globus
Departures: Apr 2025 to Sep 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 321
From (per person) 18,459
View Trip
15 Day Peru & the Galapagos Islands with Tauck
Tour + Cruise

15 Days Lima to Guayaquil
Operated By: Tauck
Departures: Apr 2025 to Oct 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 21,350
View Trip
19 Day Legacy of the Incas with Galapagos Cruise with Globus
Tour + Cruise

19 Days Lima to Guayaquil
Operated By: Globus
Departures: Feb 2025 to Sep 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 295
From (per person) 16,689
View Trip
27 Day Treasures of South America: Chilean Fjords to the Iguazu falls - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

27 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 28 February 2027
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Argentina, Chile, Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$25,468
SUITE
$29,467
Save (per person) 6,757
From (per person) 25,468
View Trip
13 Day Highlights of Peru with Galápagos Legend East Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Nov 2024 to Nov 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
26 Day Peru, Amazon & the Chilean Fjords Expedition - Cruise & Land Journey with Scenic
New ReleaseTour + Cruise

26 Days Lima to Buenos Aires
Operated By: Scenic
Ship: Scenic Eclipse I
Departure: 22 October 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Peru, Chile, Argentina
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$36,541
SUITE
$46,461
Save (per person) 6,869
From (per person) 36,541
View Trip
17 Day Peru Splendors with Peru's Amazon & Galapagos Cruise with Globus
Tour + Cruise

17 Days Lima to Guayaquil
Operated By: Globus
Departures: Feb 2025 to Dec 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
Save (per person) 213
From (per person) 12,448
View Trip
16 Day Hidden Galapagos & Peru with Tauck
Tour + Cruise

16 Days Lima to Guayaquil
Operated By: Tauck
Departure: 18 October 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
From (per person) 25,740
View Trip
13 or 14 Day Patagonia: Edge of the World with Collette
Tour + Cruise

13 or 14 Days Buenos Aires to Buenos Aires
Operated By: Collette
Departures: Oct 2024 to Mar 2026
Trip Styles: Adventure, Coach, Small Group, Cruise, Scenic
Countries Visited: Argentina, Chile
Last Minute Deal
Save (per person) 409
From (per person) 10,169
View Trip
30 Day Best of South America with Amazon and Galapagos Cruises with APT
Tour + Cruise

30 Days Santiago to Guayaquil
Operated By: APT
Ship: Delfin III
Departures: Apr 2025 to Sep 2025
Trip Styles: Coach, Group, Cruise, River Cruise, Island Hopping, Scenic
Countries Visited: Chile, Argentina, Brazil, Peru (+2 more), Ecuador, Galapagos
Exclusive DealFlash Sale
Save (per person) 3,093
From (per person) 39,302
View Trip
13 Day Highlights of Peru with Galápagos Legend North and Central Cruise with Trafalgar
Tour + Cruise

13 Days Lima to Quito
Operated By: Trafalgar
Departures: Nov 2024 to Dec 2025
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Exclusive Savings
From (per person) 10,865
View Trip
7 Day Independent Galapagos Cruise Aboard the Galapagos Legend with Globus
New ReleaseTour + Cruise

7 Days Quito to Guayaquil
Operated By: Globus
Departures: Jan 2025 to Mar 2026
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos
Exclusive Savings
Save (per person) 154
From (per person) 7,267
View Trip
17 Day Mysteries of the Inca Empire with a Galapagos Cruise with Cosmos
Tour + Cruise

17 Days Lima to Quito
Operated By: Cosmos
Departures: Mar 2025 to Dec 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Peru, Ecuador, Galapagos
Earlybird Saving
Save (per person) 278
From (per person) 10,107
View Trip
29 Day Ultimate South America with Santiago Stopover & Galapagos Cruise with Cosmos
Tour + Cruise

29 Days Santiago to Guayaquil
Operated By: Cosmos
Departures: Jan 2025 to Nov 2026
Trip Styles: Coach, Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Chile, Brazil, Argentina, Peru (+2 more), Ecuador, Galapagos
Earlybird Saving
Save (per person) 316
From (per person) 16,267
View Trip
32 Day Antarctica, Argentina & Brazil with Scenic
Tour + Cruise

32 Days Buenos Aires to Rio de Janeiro
Operated By: Scenic
Ships: Scenic Eclipse I
Departures: Feb 2025 to Feb 2026
Trip Styles: Coach, Group, Cruise, Scenic
Countries Visited: Argentina, Antarctica, South Georgia Island, Falkland Islands (+1 more), Brazil
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$45,718
SUITE
$57,370
Save (per person) 13,462
From (per person) 45,718
View Trip
36 Day Antarctic Voyage with South America and Galapagos Islands with APT
Tour + Cruise

36 Days Guayaquil to Rio de Janeiro
Operated By: APT
Departure: 01 February 2026
Trip Styles: Group, Cruise, Island Hopping, Wildlife, Scenic
Countries Visited: Ecuador, Galapagos, Peru, Argentina (+2 more), Antarctica, Brazil
Exclusive Deal
Save (per person) 2,875
From (per person) 55,520
View Trip
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