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Cruises from Miami to Panama City

Are you looking for a cruise from Miami to Panama City? December is the most popular month to cruise between Miami and Panama City and there are 9 departures available from four of the world's leading cruise lines.
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9 Cruises (9 Cruise Departures)
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 08 February 2025
Countries Visited: USA, Mexico, Belize, Guatemala (+3 more), Honduras, Costa Rica, Panama
Bonus SavingsExclusive Deal
INSIDE
$4,075
OCEANVIEW
$4,487
BALCONY
-
SUITE
-
Save (per person) 3,045
From (per person) 4,075
View Trip
11 Day CEO Loyalty Panama Canal Voyage with Azamara Cruises
Cruise
 (1)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 03 December 2024
Countries Visited: USA, Aruba, Bonaire, Curacao (+2 more), Colombia, Panama
Circle Club Voyage
INSIDE
$2,419
OCEANVIEW
$2,479
BALCONY
-
SUITE
-
From (per person) 2,419
View Trip
11 Day Panama Potpourri with Oceania Cruises
Cruise
 (2)

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Sirena
Departure: 23 March 2025
Countries Visited: USA, Bahamas, Mexico, Guatemala (+4 more), Belize, Honduras, Costa Rica, Panama
Bonus SavingsExclusive Deal
INSIDE
$3,599
OCEANVIEW
$3,874
BALCONY
$5,604
SUITE
$7,505
Save (per person) 3,221
From (per person) 3,599
View Trip
11 Day Vivid Western Caribbean with Oceania Cruises
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Oceania Cruises
Ship: Oceania Insignia
Departure: 14 April 2026
Countries Visited: USA, Mexico, Belize, Honduras (+2 more), Costa Rica, Panama
Exclusive Deal
INSIDE
$4,484
OCEANVIEW
$4,939
BALCONY
$7,315
SUITE
$10,147
Save (per person) 2,026
From (per person) 4,484
View Trip
11 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

11 Days (10 Nights) Miami to Panama City
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 12 December 2025
Countries Visited: USA, Mexico, Belize, Honduras (+3 more), Cayman Islands, Colombia, Panama
More At Sea OfferExclusive Solo Offer
INSIDE
$3,605
OCEANVIEW
$4,065
BALCONY
$5,287
SUITE
$5,671
From (per person) 3,605
View Trip
15 Day Exotic Coasts & Casco Viejo with Regent Seven Seas
Cruise

15 Days (14 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 23 February 2027
Countries Visited: USA, Mexico, Belize, Honduras (+5 more), Cayman Islands, Jamaica, Costa Rica, Colombia, Panama
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$13,033
SUITE
$13,993
Save (per person) 7,357
From (per person) 13,033
View Trip
13 Day Majestic Beaches & Canal Crossing with Regent Seven Seas
Cruise

13 Days (12 Nights) Miami to Panama City
Cruise Line: Regent Seven Seas
Ship: Seven Seas Grandeur
Departure: 03 January 2026
Countries Visited: USA, Cayman Islands, Jamaica, Bonaire (+5 more), Curacao, Aruba, Colombia, Costa Rica, Panama
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$12,581
SUITE
$13,175
Save (per person) 6,309
From (per person) 12,581
View Trip
10 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Miami to Panama City
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Jade
Departure: 01 November 2025
Countries Visited: USA, Dominican Republic, Aruba, Colombia (+1 more), Panama
More At Sea Offer
INSIDE
$3,201
OCEANVIEW
$3,660
BALCONY
$4,807
SUITE
$5,112
From (per person) 3,201
View Trip
10 Day Panama Canal - Miami with Norwegian Cruise Line
Cruise

10 Days (9 Nights) Miami to Panama City
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Gem
Departure: 02 December 2024
Countries Visited: USA, Dominican Republic, Curacao, Aruba (+1 more), Panama
More At Sea Offer
INSIDE
$1,637
OCEANVIEW
$1,713
BALCONY
$1,790
SUITE
$2,142
From (per person) 1,637
View Trip
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