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Cruises from Barcelona to Rome

Are you looking for a cruise from Barcelona to Rome? April and July are the most popular months to cruise between Barcelona and Rome and there are 124 departures available from sixteen of the world's leading cruise lines.
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62 Cruises (124 Cruise Departures)
8 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departures: Apr 2025 to Oct 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,706
OCEANVIEW
$1,946
BALCONY
$2,250
SUITE
$2,575
From (per person) 1,706
View Trip
8 Day Southern France and the Italian Riviera by Sea – with Smithsonian Journeys with Ponant
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Bougainville
Departure: 26 April 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,840
SUITE
$14,818
Save (per person) 170
From (per person) 8,840
View Trip
15 Day Malta, Greece & Amalfi Coast Collectors' Voyage with Holland America
Cruise
 (2)

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 12 July 2026
Countries Visited: Spain, Malta, Greece, Turkey (+3 more), Montenegro, Sicily, Italy
Have It All Offer
INSIDE
$3,629
OCEANVIEW
$4,223
BALCONY
$5,213
SUITE
$8,084
From (per person) 3,629
View Trip
8 Day Mediterranean with France & Italy with Princess
Cruise
 (3)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Majestic Princess
Departure: 04 March 2025
Countries Visited: Spain, Gibraltar, Corsica, Italy
Exclusive Deal
INSIDE
$1,399
OCEANVIEW
-
BALCONY
$1,385
SUITE
$1,785
From (per person) 1,385
View Trip
8 Day Europe - Western Mediterranean with Norwegian Cruise Line
Cruise
 (1)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Norwegian Cruise Line
Ship: Norwegian Epic
Departures: May 2026 to Oct 2026
Countries Visited: Spain, France, Italy, Sicily
More At Sea OfferExclusive Solo Offer
INSIDE
$2,814
OCEANVIEW
-
BALCONY
$3,426
SUITE
$3,732
From (per person) 2,814
View Trip
9 Day Spain & Italy Cruise: Barceloa, Portofino & Florence with Azamara Cruises
Cruise
 (1)

9 Days (8 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Journey
Departure: 09 April 2026
Countries Visited: Spain, France, Italy
INSIDE
$2,830
OCEANVIEW
$3,364
BALCONY
$4,374
SUITE
$6,146
From (per person) 2,830
View Trip
8 Day Mediterranean with Total Solar Eclipse with Princess
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 08 August 2026
Countries Visited: Spain, Gibraltar, Italy
Exclusive Deal
INSIDE
$2,864
OCEANVIEW
$3,636
BALCONY
$5,425
SUITE
$5,547
From (per person) 2,864
View Trip
11 Day Grand Mediterranean with Princess
Cruise
 (2)

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 11 October 2025
Countries Visited: Spain, France, Italy, Montenegro (+1 more), Greece
Exclusive Deal
INSIDE
$2,674
OCEANVIEW
$3,139
BALCONY
$4,516
SUITE
$4,902
From (per person) 2,674
View Trip
28 Day Solar Eclipse Collectors' Voyage: Iberia & Italy with Holland America
Cruise
 (2)

28 Days (27 Nights) Barcelona to Rome
Cruise Line: Holland America
Ship: Oosterdam
Departure: 02 August 2026
Countries Visited: Spain, Morocco, Portugal, Corsica (+4 more), Italy, Montenegro, Greece, Sicily
Have It All Offer
INSIDE
$7,218
OCEANVIEW
$8,109
BALCONY
$9,792
SUITE
-
From (per person) 7,218
View Trip
7 Day Mediterranean with France & Italy with Princess
Cruise
 (2)

7 Days (6 Nights) Barcelona to Rome
Cruise Line: Princess
Ship: Sun Princess
Departure: 19 March 2026
Countries Visited: Spain, Gibraltar, France, Italy
Exclusive Deal
INSIDE
$1,524
OCEANVIEW
$1,621
BALCONY
$1,938
SUITE
$2,532
From (per person) 1,524
View Trip
4 Day MSC Grand Voyages with MSC Cruises
Cruise
 (1)

4 Days (3 Nights) Barcelona to Rome
Cruise Line: MSC Cruises
Ship: MSC Orchestra
Departure: 24 March 2025
Countries Visited: Spain, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
$553
BALCONY
$708
SUITE
$1,213
From (per person) 553
View Trip
8 Day Southern France and the Italian Riviera by Sea - with Smithsonian Journeys with Ponant
Cruise
 (2)

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Ponant
Ship: Le Laperouse
Departure: 02 October 2025
Countries Visited: Spain, France, Italy
Exclusive Savings
INSIDE
-
OCEANVIEW
-
BALCONY
$8,301
SUITE
$13,907
Save (per person) 159
From (per person) 8,301
View Trip
10 Day France Intensive Voyage with Azamara Cruises
Cruise
 (1)

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Azamara Cruises
Ship: Azamara Quest
Departure: 02 April 2025
Countries Visited: Spain, France, Corsica, Italy
INSIDE
$4,277
OCEANVIEW
$4,405
BALCONY
$5,108
SUITE
$8,049
From (per person) 4,277
View Trip
8 Day A Journey to the Cote d'Azur & Olive-Scented Isles with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 08 September 2025
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Anniversary Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$7,227
SUITE
$8,217
From (per person) 6,866
View Trip
17 Day Barcelona to Civitavecchia with Silversea
Cruise

17 Days (16 Nights) Barcelona to Rome
Cruise Line: Silversea
Ship: Silver Ray
Departure: 06 July 2025
Countries Visited: Spain, France, Monaco, Italy (+1 more), Sicily
Port-to-PortDoor-to-Door Upgrade Option
INSIDE
-
OCEANVIEW
-
BALCONY
-
SUITE
$16,830
From (per person) 16,830
View Trip
31 Day Jewels Of Spain, Italy & France with Seabourn
Cruise

31 Days (30 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departure: 11 July 2025
Countries Visited: Spain, Sardinia, France, Italy (+4 more), Monaco, Sicily, Malta, Corsica
SAIL INTO SAVINGS
INSIDE
-
OCEANVIEW
-
BALCONY
$23,639
SUITE
$45,112
From (per person) 23,639
View Trip
15 Day Italy, France And Spain with Cunard
Cruise

15 Days (14 Nights) Barcelona to Rome
Cruise Line: Cunard
Ship: Queen Victoria
Departure: 18 May 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sicily
Exclusive Deal
INSIDE
$3,271
OCEANVIEW
$3,568
BALCONY
$4,063
SUITE
$8,468
From (per person) 3,271
View Trip
8 Day A Journey of Riviera Starlets & Napoleon's Corsica with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 06 October 2025
Countries Visited: Spain, France, Sardinia, Corsica (+1 more), Italy
Anniversary Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,880
SUITE
$8,118
From (per person) 6,192
View Trip
10 Day Greece, Malta & Turkey Cruise with Celebrity Cruises
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Ascent
Departure: 30 August 2025
Countries Visited: Spain, Malta, Greece, Turkey (+1 more), Italy
Exclusive Deal
INSIDE
$3,394
OCEANVIEW
$4,026
BALCONY
$3,598
SUITE
$5,966
Save (per person) 4,071
From (per person) 3,394
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 30 June 2025
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$1,898
OCEANVIEW
$2,718
BALCONY
$3,345
SUITE
$5,223
Save (per person) 936
From (per person) 1,898
View Trip
8 Day Etruscan Waterways with Oceania Cruises
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 21 April 2026
Countries Visited: Spain, France, Italy, Corsica (+1 more), Sardinia
Exclusive Deal
INSIDE
$4,030
OCEANVIEW
$4,555
BALCONY
$5,080
SUITE
$7,159
Save (per person) 2,030
From (per person) 4,030
View Trip
11 Day Greek Isles & Turkey Cruise with Celebrity Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Celebrity Cruises
Ship: Celebrity Equinox
Departures: May 2025 to Oct 2025
Countries Visited: Spain, Greece, Turkey, Italy
Exclusive Deal
INSIDE
$2,155
OCEANVIEW
$2,354
BALCONY
$2,586
SUITE
$8,117
Save (per person) 3,418
From (per person) 2,155
View Trip
11 Day Mediterranean Overture with Seabourn
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Monaco, Italy (+2 more), Corsica, Sardinia
SAIL INTO SAVINGS
INSIDE
-
OCEANVIEW
-
BALCONY
$7,777
SUITE
$15,529
From (per person) 7,777
View Trip
21 Day Spain, Morocco & Mediterranean Overture with Seabourn
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Seabourn
Ship: Ovation
Departures: May 2025 to Oct 2025
Countries Visited: Spain, France, Gibraltar, Morocco (+4 more), Monaco, Italy, Corsica, Sardinia
SAIL INTO SAVINGS
INSIDE
-
OCEANVIEW
-
BALCONY
$14,115
SUITE
$30,688
From (per person) 14,115
View Trip
11 Day Blooming Mediterranean with Oceania Cruises
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Oceania Cruises
Ship: Oceania Marina
Departure: 08 May 2025
Countries Visited: Spain, Tunisia, Malta, Greece (+2 more), Sicily, Italy
Bonus SavingsExclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$6,579
SUITE
$9,600
Save (per person) 2,791
From (per person) 6,579
View Trip
21 Day An Extended Journey Into The Mediterranean’s Coveted Cultures with Explora Journeys
Cruise

21 Days (20 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departure: 03 April 2025
Countries Visited: Spain, Morocco, Gibraltar, Sardinia (+3 more), Tunisia, Sicily, Italy
Anniversary Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$16,196
SUITE
$18,216
From (per person) 16,196
View Trip
10 Day Plazas & Colonnades with Regent Seven Seas
Cruise

10 Days (9 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 10 April 2026
Countries Visited: Spain, France, Monaco, Italy (+2 more), Corsica, Sicily
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$8,140
SUITE
$9,843
Save (per person) 5,820
From (per person) 8,140
View Trip
11 Day Spotlight On Aston Martin Aramco with Regent Seven Seas
Cruise

11 Days (10 Nights) Barcelona to Rome
Cruise Line: Regent Seven Seas
Ship: Seven Seas Splendor
Departure: 22 July 2025
Countries Visited: Spain, France, Monaco, Italy
Exclusive Deal
INSIDE
-
OCEANVIEW
-
BALCONY
$14,198
SUITE
$15,089
Save (per person) 10,682
From (per person) 14,198
View Trip
8 Day A Journey of Golden Ibiza Days & Warm Riviera Nights with Explora Journeys
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Explora Journeys
Ship: Explora II
Departures: Jun 2025 to Aug 2025
Countries Visited: Spain, France, Italy
Anniversary Offer
INSIDE
-
OCEANVIEW
-
BALCONY
$6,880
SUITE
$8,217
From (per person) 6,311
View Trip
8 Day Western Mediterranean Cruise with Royal Caribbean
Cruise

8 Days (7 Nights) Barcelona to Rome
Cruise Line: Royal Caribbean
Ship: Voyager of the Seas
Departure: 22 September 2025
Countries Visited: Spain, France, Corsica, Italy
Exclusive Deal
INSIDE
$1,422
OCEANVIEW
$1,668
BALCONY
$2,219
SUITE
$3,328
Save (per person) 712
From (per person) 1,422
View Trip
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